Why is periodontal disease more prevalent and more severe in people with Down syndrome?
Identifieur interne : 000398 ( Main/Exploration ); précédent : 000397; suivant : 000399Why is periodontal disease more prevalent and more severe in people with Down syndrome?
Auteurs : James MorganSource :
- Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry [ 0275-1879 ]
Descripteurs français
- KwdFr :
- Gingivite ulcéronécrotique (étiologie), Humains (MeSH), Hygiène buccodentaire (MeSH), Lymphocytes T (immunologie), Maladies parodontales (immunologie), Maladies parodontales (étiologie), Matrix metalloproteinases (métabolisme), Médiateurs de l'inflammation (métabolisme), Syndrome de Down (complications), Syndrome de Down (immunologie).
- MESH :
- immunologie : Lymphocytes T, Maladies parodontales, Syndrome de Down.
- métabolisme : Matrix metalloproteinases, Médiateurs de l'inflammation, Syndrome de Down.
- étiologie : Gingivite ulcéronécrotique, Maladies parodontales.
- Humains, Hygiène buccodentaire.
English descriptors
- KwdEn :
- Down Syndrome (complications), Down Syndrome (immunology), Gingivitis, Necrotizing Ulcerative (etiology), Humans (MeSH), Inflammation Mediators (metabolism), Matrix Metalloproteinases (metabolism), Oral Hygiene (MeSH), Periodontal Diseases (etiology), Periodontal Diseases (immunology), T-Lymphocytes (immunology).
- MESH :
- chemical , metabolism : Inflammation Mediators, Matrix Metalloproteinases.
- complications : Down Syndrome.
- etiology : Gingivitis, Necrotizing Ulcerative, Periodontal Diseases.
- immunology : Down Syndrome, Periodontal Diseases, T-Lymphocytes.
- Humans, Oral Hygiene.
Abstract
Periodontal disease has been found to be significantly more prevalent and more severe in people with Down syndrome. A series of studies have reported a prevalence of between 58% and 96% for persons younger than 35 years of age. This phenomenon cannot simply be attributed to poor oral hygiene. The etiology of periodontal disease in persons with Down syndrome is complex. In recent years, much focus has been placed on the altered immune response resulting from the underlying genetic disorder. This paper presents an overview of contemporary knowledge on periodontal disease in patients with Down syndrome.
DOI: 10.1111/j.1754-4505.2007.tb00346.x
PubMed: 17990479
Affiliations:
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Le document en format XML
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A series of studies have reported a prevalence of between 58% and 96% for persons younger than 35 years of age. This phenomenon cannot simply be attributed to poor oral hygiene. The etiology of periodontal disease in persons with Down syndrome is complex. In recent years, much focus has been placed on the altered immune response resulting from the underlying genetic disorder. 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